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PureFocus™690 Laser Autofocus System


Hardware Laser Autofocus for Raman and IR Microscopy

PureFocus690 combines advanced optics and intelligent microprocessing with a 690 nm laser. Designed primarily for infrared imaging, the system will transmit up to 1100 nm and all the major Raman microscopy excitation wavelengths.

It provides a real-time focus system for infinity-corrected optical systems and offers sample detection, dynamic power adjustment, and long focus recapture range.

A motorized offset lens allows adjustment of the imaging depth into the sample, continuously holding the precise distance between the imaging focal point and a reference interface of choice or enabling different discrete image planes to be acquired using the same interface. 

Designed for versatility and mounted in the infinity space, it is compatible with most brands of commercial microscopes, Prior’s OpenStand imaging platform, Queensgate piezo devices, and can be adapted for third-party focus actuators


    • Rapid automated focus recovery for numerous applications.
    • Integrated stepper motor driver and interface to Piezo and other actuators via 0-10 V analog output.
    • Easily adapted to any infinity optical system, both upright and inverted.
    • Stores and recalls multiple objective-specific parameters for multi-objective use.
    • Customizable optics for specific imaging applications.
Product Code PF690 PF690M
Dichroic clear aperture, diameter 32 mm 32 mm
Laser optical output < 0.77 mW < 0.77 mW
Laser class Class 1 Class 1
Laser wavelength 690 nm 690 nm
Focus accuracy 20 % of DOF 20 % of DOF
Surface tracking method Point on surface tracking Averaged surface tracking
Typical update rate 1 kHz 1 kHz
Transmitted wavelength range 385-650 nm | 730-1100 nm 385-650 nm | 730-1100 nm
Capture speed (5x, 0.13NA) < 30 ms < 30 ms
Capture speed (10x, 0.4NA) < 50 ms < 50 ms
Capture speed (20x, 0.5NA) < 60 ms < 60 ms
Capture speed (40x, 0.95NA) < 100 ms < 100 ms
Capture speed (100x, 0.9NA) < 1500 ms < 1500 ms
Capture range (5x, 0.13NA) +/- 15000 μm +/- 15000 μm
Capture range (10x, 0.4NA) +/- 3000 μm +/- 3000 μm
Capture range (20x, 0.5NA) +/- 1000 μm +/- 1000 μm
Capture range (40x, 0.95NA) +/- 500 μm +/- 500 μm
Capture range (100x, 0.9NA) +/- 100 μm +/- 100 μm
Laser module mass 1.5 kg 1.5 kg

Specifications as per datasheet. Please see datasheet for details.

  • PF209 PureFocus Setup Sample Slide

  • PF300 PureFocus Setup Camera

  • PF200 PureFocus Setup Target (RMS, W26, M32 threads)

  • PF201 PureFocus Setup Target (M25, M27, M32 threads)

  • PF404 Piezo Cable for PF850 15D to BNC

Option Manufacturer Compatibility Notes

PF690(M)

+ LF335

Evident/Olympus BX53M, MX50, MX51, MX61, MX61L, MX63, MX63L

PF690(M)

+ LF320

Nikon LV100ND, LV100NDA, LV150N, LV150NA, L200N, L200ND, L300N, L300ND, Ni-U

PF690(M)

+ LF335

Prior OpenStand-U, OpenStand-M, OpenStand-L, OpenStand-V

PF690(M)

+ PF208

Evident/Olympus IX73 (2-deck) Contact Prior Scientific if both decks are occupied

PF690(M)

+ PF214

Evident/Olympus IX73 (1-deck)

PF690(M)

+ PF203

Evident/Olympus IX71

PF690(M)

+ PF213

Evident/Olympus IX81

PF690(M)

+ PF211

Nikon Ti-U

PF690(M)

+ PF212

Nikon Ti2-U, Ti2-A Contact Prior Scientific for Ti2-E

PF690(M)

+ PF210

Evident/Olympus BX51, BX53

PF690(M)

+ LF341

Zeiss AxioSkop 40 Please check with Prior Scientific for Axioimager models

PF690(M)

+ LF312

Leica DM4000, DM5000, DM6000, DM6

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